Registration Dossier
Registration Dossier
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EC number: 202-496-6 | CAS number: 96-29-7
Endpoint summary
Administrative data
Description of key information
Additional information
Butanone oxime has a low log Pow of 0.63 and, based on the low octanol water partition coefficient, a low adsorption potential of the substance is expected. The water solubility determined for the substance is 100 g/L at 25 °C and pH ~7. Based on these characteristics adsorption to soil and suspended matter is not expected. The potential of acute or chronic toxicity to terrestrial organisms is considered to be low. Although the substance is not readily biodegradable (14.5% degradation after 28 days, OECD 301C) a potential for inherent degradation was demonstrated in a study following OECD Guideline 302B (70% degradation after 14d). Based on the low adsorption potential and the assessment as inherently biodegradable, not fulfilling specific criteria, a chronic exposure of sediment organisms is considered unlikely. A QSAR calculation using the Persistence (soil) model (IRFMN) 1.0.0, included in the VEGA software version 1.1.4, predicted “not P” for the substance.
Therefore, Butanone oxime can be assigned to Soil Hazard category 3 (ITS-strategy, terrestrial toxicity, ECHA Guidance R.7c) based on the low adsorption potential (log Kow <3) in combination with no indication of a very high toxicity to aquatic organisms (EC/LC50 > 1 mg/L). The available screening assessment based on EPM shows no concern for the terrestrial compartment (all RCR< 1; please refer to Chapter 9 and 10 of the Chemical Safety Report for detailed information).
Based on the available data and the conducted screening assessment no toxicity testing for soil organisms need to be done.
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