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Acute tests on all three trophic levels were performed to examine the acute aquatic toxicity of 2-(2-aminoethylamino)ethanol.

Daphnia magna turned out to be the most sensitive species with an EC50 of 22 mg/L after a 48 hour exposure period. Effects of 2-(2-aminoethylamino)ethanol towards fish and algae were found at a LC50 (96h) of 640 mg/l and an ErC50 (72h) of 353.6 mg/l, respectively.

Thus, 2-(2-aminoethylamino)ethanol is considered to be acutely harmful for aquatic organisms.