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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Hydrolysis

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Administrative data

Link to relevant study record(s)

Description of key information

The registered substance exhibits an estimated half-life of 139 d for pH 7 at 25°C (calculated from experimental data at 50, 65 and 80°C) and has to be considered as stable to hydrolysis

Key value for chemical safety assessment

Half-life for hydrolysis:
139 d
at the temperature of:
25 °C

Additional information

The test material was insoluble in water (far from 100 mg/L). Thus, test material meets the definition of poorly water soluble substances and has to be considered as a "difficult substance to test" according to OECD Guidance No 23 (2000) on aquatic toxicity testing of difficult substances and mixtures. A hydrolysis study has been performed according to OECD TG 111. The results of Tier 1 (50°C) indicated that HDI Trimer MEKO-blocked was unstable to hydrolysis. Tier 2 testing was performed at three pH and three temperatures (higher ones for pH 7 and 9). HDI Trimer MEKO-blocked exhibits an estimated half-life of 139 d for pH 7 at 25 °C (calculated from experimental data at 50, 65 and 80 °C).