Registration Dossier
Registration Dossier
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EC number: 203-401-0 | CAS number: 106-47-8
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- other: lit.search data
- Rationale for reliability incl. deficiencies:
- other: Data from handbook of collection of data.
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- No information
- Year:
- 2 003
- Bibliographic source:
- International Programme on Chemical Safety's Concise International Chemical Assessment Documents. Number 48: 4-Chloroaniline (2003). Available from, as of February 22, 2005: http://www.inchem.org/pages/cicads.html
Materials and methods
- Principles of method if other than guideline:
- No guideline known, only database endpoints.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-chloroaniline
- EC Number:
- 203-401-0
- EC Name:
- 4-chloroaniline
- Cas Number:
- 106-47-8
- Molecular formula:
- C6H6ClN
- IUPAC Name:
- 4-chloroaniline
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
Results and discussion
In vivo
- Irritant / corrosive response data:
- In OECD guideline studies PCA was found to be non-irritating to rabbit skin.
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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