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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Data Sheet for CAS: 112-15-2
Author:
Industrial Medicine and Toxicology Dept., Union Carbide Corp
Year:
1965
Bibliographic source:
Union Carbide Data Sheet. (Industrial Medicine and Toxicology Dept., Union Carbide Corp., 270 Park Ave., New York, NY 10017) 7/20, 1965.
Reference Type:
review article or handbook
Title:
DPIM: CBQ750
Author:
Richard J. Lewis, Sr.
Year:
2007
Bibliographic source:
SAX (Sax's Handbook of Dangerous Industrial Materials)Union Carbide Data Sheet. (Industrial Medicine and Toxicology Dept., Union Carbide Corp., 270 Park Ave., New York, NY 10017) 7/20, 1965.

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
standard acute method
GLP compliance:
not specified
Test type:
standard acute method

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(2-ethoxyethoxy)ethyl acetate
EC Number:
203-940-1
EC Name:
2-(2-ethoxyethoxy)ethyl acetate
Cas Number:
112-15-2
Molecular formula:
C8H16O4
IUPAC Name:
2-(2-ethoxyethoxy)ethyl acetate
Details on test material:
- Name of test material: 2-(2-ethoxyethoxy) ethyl acetate
- Substance type: Organic
- Physical state: Liquid

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Duration of exposure:
not reported
Doses:
not reported
No. of animals per sex per dose:
not reported
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
15 100 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Dermal toxicity of 2-(2-ethoxyethoxy) ethyl acetate (LD50) to rabbit was examined at dose concentration of 15100 mg/kg body weight.
Executive summary:

Dermal toxicity of 2-(2-ethoxyethoxy) ethyl acetate (LD50) to rabbit was examined at dose concentration of 15100 mg/kg body weight. This value suggests that the chemical will not exhibit acute toxicity to rabbit by the dermal route.