Registration Dossier

Administrative data

Endpoint:
additional toxicological information
Type of information:
(Q)SAR
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: (Q)SAR is in silico prediction tool
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6
Cross-referenceopen allclose all
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study

Data source

Materials and methods

Type of study / information:
(Q)SAR method report
Principles of method if other than guideline:
none
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): 2-Chloromethyl-4-methoxy-3,5-dimethylpyridine hydrochloride
- Purity test date: 20. 02. 2008
- Lot/batch No.: 30000859
- Expiration date of the lot/batch: 01. 2009

Results and discussion

Any other information on results incl. tables

See Applicant's summary and discussion

Applicant's summary and conclusion

Conclusions:
According to (Q)SAR method, the substance:
may be a potential mutagen, examples tested possitive in Ames test
may be potential irritatant of skin, eyes and respiratory tract, may cause corrosion
has a low cardiac toxicity risk
is unlikely to have drug-drug interactions
is unlikely to cause photoirritations
had no in silico metabolic allerts
Executive summary:

None