2,5-dimethylhexane-2,5-diol

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Guideline study with acceptable restrictions

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1989

Report date:

1989

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: German Industrial Standard DIN 38412 part 15

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

DMHD solution

IUPAC Name:

DMHD solution

Details on test material:

- Name of test material (as cited in study report): DMHD
- Physical state: liquid
- Analytical purity: no data

Sampling and analysis

Analytical monitoring:

no

Test solutions

Vehicle:

no

Test organisms

Test organisms (species):

Leuciscus idus

Details on test organisms:

TEST ORGANISM
- Common name: golden orfe
- Source: Fischzucht Paul Eggers, Hohenwestedt, Germany
- Length at study initiation (length definition, mean, range and SD): 7.2 cm (6.2 - 7.9 cm)
- Weight at study initiation (mean and range, SD): 3.5 g (2.4 - 4.4 g)
- Feeding during test: none


ACCLIMATION
- Acclimation period: 3 months
- Acclimation conditions (same as test or not): yes
- Type and amount of food: grwoing feed F/B 50
- Health during acclimation (any mortality observed): no

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

96 h

Test conditions

Details on test conditions:

TEST SYSTEM
- Test vessel:
- Type (delete if not applicable): open
- Material, size, headspace, fill volume: 10l all glass aquaria
- Aeration: slight
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 1
- No. of vessels per control (replicates): 1
- No. of vessels per vehicle control (replicates): none
- Biomass loading rate: 3.5 g fish/l


OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: 16:8

Reference substance (positive control):

yes

Remarks:

chloracetamid

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

4 600 - 10 000 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Effect concentrations 2

Duration:

96 h

Dose descriptor:

NOEC

Effect conc.:

2 150 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

behaviour

Applicant's summary and conclusion

Validity criteria fulfilled:

yes