Registration Dossier
Registration Dossier
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EC number: 402-070-1 | CAS number: 88122-99-0 UVINUL T 150
Endpoint summary
Administrative data
Description of key information
Toxicity(Oral):LD 50 > 5000 mg/kg bw (OECD 401, GLP)
Toxicity(Dermal):LD 50 > 2000 mg/kg bw (OECD 402, GLP)
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 401 (1981)
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
- Route of administration:
- oral: unspecified
- Vehicle:
- other: 0.5% aqueous carboxymethylcellulose
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Mortality:
- Male : 5000mg/kg bw; number of animals : 5 ; number of deaths : 0
Female : 5000mg/kg bw; number of animals : 5 number of deaths : 0 - Clinical signs:
- other:
- Gross pathology:
- Effects on organs : No conspicuous findings
- Interpretation of results:
- other: not classified Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Not classified
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- > 5 000 mg/kg bw
Acute toxicity: via inhalation route
Link to relevant study records
- Endpoint:
- acute toxicity: inhalation
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because exposure of humans via inhalation is not likely taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Link to relevant study records
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 402 (1981)
- GLP compliance:
- yes
- Limit test:
- yes
- Species:
- rat
- Strain:
- other: common species
- Sex:
- male/female
- Type of coverage:
- semiocclusive
- Vehicle:
- olive oil
- Duration of exposure:
- 24 h
- Control animals:
- not specified
- Key result
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male : 2000 mg/kg bw ; number of animals : 5 ; number of deaths : 0
Female : 2000 mg/kg bw ; number of animals : 5 ; number of deaths : 0 - Clinical signs:
- other:
- Gross pathology:
- Effects on organs : No conspicuous findings
- Other findings:
- Signs of toxicity (local) : No conspicuous findings
- Interpretation of results:
- other: not classified Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- not classified
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- > 2 000 mg/kg bw
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
