Registration Dossier
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EC number: 939-464-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 990
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: APHA method (1980)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- triethanolamine
- IUPAC Name:
- triethanolamine
- Reference substance name:
- 2,2',2''-nitrilotriethanol
- EC Number:
- 203-049-8
- EC Name:
- 2,2',2''-nitrilotriethanol
- Cas Number:
- 102-71-6
- Molecular formula:
- C6H15NO3
- IUPAC Name:
- 2,2',2''-nitrilotriethanol
- Details on test material:
- - Name of test material (as cited in study report): Triethanolamine
- Analytical purity: 97 %
Constituent 1
Constituent 2
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- - concentrations were analysed by gas-liquid chromatography (GLC)
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Pimephales promelas
- Details on test organisms:
- Test species: Fathead minnow (Pimephales promelas)
- age (d): 30
- mean body length (mm): 18.1 ± 0.788
- mean weight (g): 0.083 ± 0.0083
- loading (g/l): 0.1153
Study design
- Test type:
- flow-through
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- 25.7 ± 0.38 °C
- pH:
- 7.8 ± 0.07
- Dissolved oxygen:
- 7.3 mg/l
- Nominal and measured concentrations:
- Nominal test concentrations (g/l): 0, 7.30, 11.2, 17.3, 26.6, and 40.9
test substance recovery by GLC: 107.2 ± 3.8% (n = 4) - Details on test conditions:
- TEST SYSTEM
- Test vessel: 20 fish/concentration
- tank volume (l): 1.0 (additions 14.4 v/d)
- pH: the pH of the stock solution (90.4 mg/l) was adjusted to that of lake water using HCl. - Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 11 800 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Reported statistics and error estimates:
- The estimated LC/EC50 values with corresponding 95% confidence intervals were calculated using the corrected average of the analyzed tank concentrations and the Trimmed Spearman-Kaerber method (Hamilton et al., 1977).
Any other information on results incl. tables
- Sublethal observations / clinical signs:
Effect values (related to measured concentrations): 96-h EC50 (g/l): 11.8 (10.6-13.0)
Mortalities
Nominal conc (g/l)
Mean measured (corr.)
No. of fish at start
Dead fish after
24h
48h
72h
96h
Control
< 0.02
20
0
0
0
0
7.30
6.14
20
0
0
0
0
11.2
9.86
20
1
3
4
4
17.3
15.4
20
15
17
18
18
26.6
24.4
20
20
20
20
20
40.9
38.1
20
20
20
20
20
Physiological/behavioral effects
Affected fish showed loss of schooling behaviour, hyperactivity, dark coloration, increased respiration and loss of equilibrium prior to death.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 96 h LC50 was 11800 mg/L based on measured concentrations.
- Executive summary:
Acute toxicity of TEA to fathead minnows was tested according to APHA method (1980). No mortaility was observed in the control.
Affected fish showed loss of schooling behaviour, hyperactivity, dark coloration, increased respiration and loss of equilibrium prior to death.
Effect values (related to measured concentrations): 96-h LC50 (g/l): 11.8 (10.6-13.0)
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