Registration Dossier

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The 3-h EC50 of C12-18 (even numbered), N-[3-(dimethylamino) propyl], N'-oxides to activated sludge microorganisms was found to be 970 mg/L. The EC50 was used for derivation of the PNEC. An assessment factor of 100 was used as specified in ECHA (2008) for sludge inhibition EC50 values .

Key value for chemical safety assessment

EC50 for microorganisms:
970 mg/L
EC10 or NOEC for microorganisms:
32 mg/L

Additional information

A 3-h Activated Sludge Respiration Inhibition Test was conducted according to OECD Guideline 209 and GLP. The inoculum used was activated sludge of a predominantly domestic sewage. Concentrations tested were Control, 10, 100 and 1000 mg/L. The reference substance result was within required range, and control variability was valid. The 3-h EC50 of C12-18 (even numbered), N-[3-(dimethylamino) propyl], N'-oxides to activated sludge was found to be 970 mg/L. The NOEC was 32 mg/L.