Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 403-710-2 | CAS number: 76823-93-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
seek medical attention. In all cases, remove contaminated
clothing and wash before re-use
Emergency measure - Eyes: Immediately flush with plenty of water, seek medical
attention
Emergency measure - Skin: Wash with soap and water
Emergency measure - Ingestion: Seek medical attention (A physician may wish to advise the
use of a gastric lavage. However, the substance is not
corrosive)
Fire-fighting measures
oxides together with some ammonia and hydrogen cyanide gas.
A self-contained breathing apparatus should be used.
Suitable extinguishing agents are dry powder, water, carbon
doxide, foam or Halon
Product determined by test: Y
Accidental release measures
Handling and storage
of dust. Wear suitable protective glasses and rubber gloves
and handle under local exhaust ventilation. A cup type mask
(BS 6016) filtering to 5 micron is recommended when little
exposure is expected. If heavier exposure is anticipated, a
half-face mask with Class P2 filter conforming to DIN 3181
is recommended. In extreme cases of dust inhalation, the
symptoms are as for a cold and last a few days
Storage: Store at ambient temperature in tightly closed polythene
bags in fibre drums. Protect from light as much as possible
Transport information
Shippingopen allclose all
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
Shippingopen allclose all
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
Shippingopen allclose all
Special provisions / remarks
- Remarks:
- Transport: Transport in tightly closed polythene bags inside fibre
drums
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Stability and reactivity
Chemical reaction with water: Limited solubility in water, no reaction.
Disposal considerations
converted during use to a pharmaceutical active ingredient
Industry - Possibility of neutralisation: Neutralisation would not be necessary.
Industry - Possibility of destruction: controlled discharge: Not recommended
Industry - Possibility of destruction - incineration: Recommended. Waste gas treatment to remove nitrogen and
sulphur oxides, ammonia and hydrogen cyanide gas should be
used
Industry - Possibility of destruction - water purification: Traces of the substance may be present in mother liquors and
these should not provide any undue problems for a waste
water treatment plant. However the substance itself, which
is not readily biodegradable, should not be discharged to
the aqueous environment in bulk.
Public at large - Possibility of recovery/recycling: The substance will not enter the public domain
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.