Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Screening method (Pretest Quality)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report date:
2000

Materials and methods

Principles of method if other than guideline:
Screening method based on the detection of the beginning of precipitate formation upon portion-wise addition of an organic solution of the test substance under continuous stirring into an excess volume of water while maintaining a temperature range of 25 to 30 °C.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
17 beta-Acetoxy-5 alpha-androstan-3-one
EC Number:
601-431-2
Cas Number:
1164-92-7
Molecular formula:
C21 H32 O3
IUPAC Name:
17 beta-Acetoxy-5 alpha-androstan-3-one

Results and discussion

Water solubility
Water solubility:
0.003 g/L
Remarks on result:
other: pretest type data, Temperature 25 to 30°C, pH not determined

Applicant's summary and conclusion

Executive summary:

The water solubility of androstanolon-acetat was determined in “pretest quality” to be

0.003 g/l

using a screening method based on the detection of the beginning of precipitate formation upon portion-wise addition of an organic solution of the respective test substance under continuous stirring into an excess volume of water while maintaining a temperature range of 25 to 30 °C.

Due to the specifics of the screening method, the above value is expected to represent an upper limit which should not be exceeded by the test substance in its crystalline form.

Androstanolon-acetat is to be considered as practically insoluble or insoluble in water.