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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

Currently viewing:

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary literature

Data source

Reference
Reference Type:
review article or handbook
Title:
Phenol and Phenolics
Author:
Gingell et al.
Year:
2001
Bibliographic source:
Patty´s Toxicology, John Wiley & Sons, p 11

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Acute dermal study was conducted in rats
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
4-chlorophenol
EC Number:
203-402-6
EC Name:
4-chlorophenol
Cas Number:
106-48-9
Molecular formula:
C6H5ClO
IUPAC Name:
4-chlorophenol
Details on test material:
- Name of test material (as cited in study report): 4-chlorophenol
- Analytical purity: no data

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Duration of exposure:
no data
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not required

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 500 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
CLP: Acute tox.4, H312
DSD: Xn, R21