Registration Dossier

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
23.10-31.10.2007
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline, available as an unpublished report, limitations in reporting but otherwise adequate for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Mixture of aromatic hydrocarbons C6-C8 (>60%) with aliphatic hydrocarbons C5-C9

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
2.2 - 6.5
Temp.:
23 °C
pH:
6.2
Details on results:
59 area% from log Pow = 2.2 to log Pow = 3.0, 39 area % from log Pow >3.0 to log Pow = 6.1, 1.9 area % log Pow >6.5. Main component 1 (33 area %): log Pow = 2.2. Main component 2 (26 area %): log Pow = 2.8

Applicant's summary and conclusion

Conclusions:
CAS number 68475 -70 -7 consists of a mixture of compounds woth log Pow values in the range from log Pow = 2.2 to > 6.5
Executive summary:

CAS number 68475 -70 -7 consists of a mixture of compounds woth log Pow values in the range from log Pow = 2.2 to > 6.5. This study is GLP compliant and follows a standard guideline. It is reliable and suitable for use as a key study.