Registration Dossier

Administrative data

Link to relevant study record(s)

Description of key information

Anaerobic ready and ultimate biodegradation of dimethyl sulfide in natural sediment/water slurry (50%/50% w/w) has been shown. The DMS half-life in the gas phase, after addition at 1.2 mmol/l above anaerobic natural water/sediment slurry from Big Soda Lake (Nevada), was between 4 to 5 days and it disappeared totally after 7 days.

Key value for chemical safety assessment

Additional information

Dimethyl sulphide being readily biodegradable, higher-tier tests about its biodegradability potential are not required according to REACH. Nevertheless, references have been identified and are included in the characterization of dimethyl sulphide.

Kiene (1986) is a non-GLP-compliant study following a similar protocol to OECD guideline 308. The experiments are well described and driven according described protocols. The study is considered reliable and suitable for use for this endpoint.

This is supported by Oremland (1989), a non-guideline study following scientific principles. The experiment shows that a pure strain culture can grow on DMS as source of carbon and these results support the general conclusion that the substance can be biodegraded. However, the study is not relevant for a risk assessment according to current guidelines.

This is supported by Kanagwa (1986), a non-GLP, non-guideline study following scientific principles, giving oxidation kinetics by a pure strain culture. The results support the general conclusion that the substance can be biodegraded. However the study is considered not relevant for a risk assessment according to current guidelines.

This is supported by Zinder (1978), a non-GLP compliant, non-guideline study following scientific principles. The study uses radiolabelled carbon to measure the methane and carbon dioxide production from the degradation of dimethyl sulphide in anaerobic sediment. The result support other studies on anaerobic biodegradation, but study duration not suitable for the dossier purpose. The study is therefore only used as supporting data for this endpoint.