Registration Dossier
Registration Dossier
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EC number: 209-980-6 | CAS number: 600-00-0
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Two in-vitro and one in-vivo experimental studies have shown that ethyl 2-bromoisobutyrate induced reverse mutation in salmonella typhimurium and micronuclei in the polychromatic erythrocytes of the bone marrow of mice.
Short description of key information:
Ethyl 2-bromoisobutyrate has to be considered as mutagen since 3 experimental studies carried on the topic conclude in the presence of a risk on gene mutation
Endpoint Conclusion: Adverse effect observed (positive)
Justification for classification or non-classification
Ethyl 2-bromoisobutyrate has to be considered as Mutagen. The hazard statement Mutagen cat.1B and the sentence H340 "May cause genetic defects" are then required.
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