Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

Two in-vitro and one in-vivo experimental studies have shown that ethyl 2-bromoisobutyrate induced reverse mutation in salmonella typhimurium and micronuclei in the polychromatic erythrocytes of the bone marrow of mice.

Short description of key information:
Ethyl 2-bromoisobutyrate has to be considered as mutagen since 3 experimental studies carried on the topic conclude in the presence of a risk on gene mutation

Endpoint Conclusion: Adverse effect observed (positive)

Justification for classification or non-classification

Ethyl 2-bromoisobutyrate has to be considered as Mutagen. The hazard statement Mutagen cat.1B and the sentence H340 "May cause genetic defects" are then required.