Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
immunotoxicity
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)

Data source

Reference
Title:
No information
Author:
Vos, J.G. et al: Methods for testing immune efects of toxic chemicals: Evaluation of the immunotoxicity ofvarious pesticides in the rat,|Hum. Welfare Environment Proc. Int. Congr. Pestic. Chem., Vol 3, 497-504 (1983)

Materials and methods

GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Diuron
EC Number:
206-354-4
EC Name:
Diuron
Cas Number:
330-54-1
Molecular formula:
C9H10Cl2N2O
IUPAC Name:
3-(3,4-dichlorophenyl)-1,1-dimethylurea

Test animals

Species:
rat
Strain:
Wistar
Sex:
male

Administration / exposure

Route of administration:
other: ral in feed
Vehicle:
other: none
Frequency of treatment:
3 weeks
Doses / concentrations
Remarks:
Doses / Concentrations:
25, 250, 2500 mg/kg feed
Basis:

No. of animals per sex per dose:
6

Results and discussion

Any other information on results incl. tables

Result: not immunotoxic

Applicant's summary and conclusion