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Diss Factsheets

Administrative data

Endpoint:
immunotoxicity
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)

Data source

Reference
Title:
No information
Author:
Vos, J.G. et al: Methods for testing immune efects of toxic chemicals: Evaluation of the immunotoxicity ofvarious pesticides in the rat,|Hum. Welfare Environment Proc. Int. Congr. Pestic. Chem., Vol 3, 497-504 (1983)

Materials and methods

GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Diuron
EC Number:
206-354-4
EC Name:
Diuron
Cas Number:
330-54-1
Molecular formula:
C9H10Cl2N2O
IUPAC Name:
3-(3,4-dichlorophenyl)-1,1-dimethylurea

Test animals

Species:
rat
Strain:
Wistar
Sex:
male

Administration / exposure

Route of administration:
other: ral in feed
Vehicle:
other: none
Frequency of treatment:
3 weeks
Doses / concentrations
Remarks:
Doses / Concentrations:
25, 250, 2500 mg/kg feed
Basis:

No. of animals per sex per dose:
6

Results and discussion

Any other information on results incl. tables

Result: not immunotoxic

Applicant's summary and conclusion

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