Registration Dossier
Registration Dossier
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EC number: 305-500-5 | CAS number: 94581-02-9 Coke formed by cooling, to approximately 1500°C, hot acetylene containing split gases from aromatic residual oil produced from ethylene production by naphtha cracking at 800°C to 900°C (427°F to 482°F) (coal derived).
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Skin irritation
Skin irritation was tested using an internal standard method (BASF, 1978). This study meets scientific standards with acceptable restrictions (limited documentation).
Two White Vienna rabbits were treated for 1, 5 and 15 minutes and for 20 hours using occlusive conditions. An application site of 2.5 x 2.5 cm was covered with the test substance.The test substance induced erythema after 20 h occlusive exposure (reversibel within 7 d) in 1/2 animals; 15 min exposure did not cause any irritation effects.
Eye irritation
Eye irritation was tested in a study comparable to OECD Guideline 405 with acceptable restrictions (BASF AG, 1978). 50 mg of the test substance were applied to the conjunctival sac of one eye of 2 animals. The talcum-treated adjacent eye served as a control.
Corneal opacity and iritis were not observed; slight chemosis was observed only at the day of application. Conjunctivae redness was observed in both animals as reversible effect within one and eight days, respectively. Effects observed were equivalent to the effects of the negative control (talcum).
Justification for classification or non-classification
Classification is not warranted according to the criteria of EU Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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