Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Recent study according to OECD guidelines.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
not specified
GLP compliance:
no
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
m-(4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzenesulphonic acid
EC Number:
204-303-0
EC Name:
m-(4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzenesulphonic acid
Cas Number:
119-17-5
Molecular formula:
C10H10N2O4S
IUPAC Name:
3-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzene-1-sulfonic acid

Results and discussion

Water solubility
Water solubility:
4.3 g/L
Temp.:
20 °C
pH:
ca. 1.9

Any other information on results incl. tables

Preliminary test:

ml of water for 0,1 g soluble

0.1

0.5

1

2

10

100

150

approx. solubility in g/1

>1000

1000 to
200

200 to
100

100 to 50

50 to 10

10 to 1

<1

visual evaluation

not
soluble

not
soluble

not
soluble

not
soluble

not
soluble

soluble

soluble

 

Solubility test:

Three flasks containing approx. 50 g/1 test substance in water were stirred for 5 h at 30 °C. Subsequently the flasks were stirred at 20 °C for 1 day, 2 days and 3 days respectively. After each day the content of one flask was filtered through a 0.2 µm membrane filter . The content of the test substance in the filtrate was determined by UV/VIS spectroscopy.

Flask No.

Equilibration time
at 20 °C

[h]

pH of aqueous
solution

Test substance
content
[g/l]

1

2

3

24
48
72

1.9
1.9
1.9

4.25
4.37
4.31

mean

 

---

4.31

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L)
The water solubility of the item is 4.3 g/L at 20°C.
Executive summary:

The water solubility of the test substance Pyrazolic acid 3 was determined according to theOECD Guideline for the Testing of Chemicals 105.

Result:

Water solubility (20 °C):           4.3 g/l