Registration Dossier
Registration Dossier
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EC number: 234-373-8 | CAS number: 11129-15-0
Carcinogenicity
Administrative data
Description of key information
No carcinogenicity data are currently available for calcium zirconium oxide. Nevertheless, from the data available on zirconium dioxide (which is present at >= 90% in the crystal lattice of calcium zirconium oxide), it can be concluded that testing is not required as zirconium dioxide is not mutagenic and no evidence of hyperplasia or pre-neoplastic lesions is observed from the repeated dose studies. Additionally, the presence of calcium in the crystal lattice is not expected to alter the non-hazardous toxicological profile of zirconium dioxide as calcium is omnipresent throughout the human body and is essential to living organisms. As is the case for zirconium dioxide, there is no evidence for calcium oxide to cause systemic adverse effects.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
