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EC number: 406-940-1 | CAS number: 126019-82-7 DP 211
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Due to very low water solubility an experimental study was not conducted. However, the substance has functional groups which could hydrolyse.
According to QSAR calculations the substance hydrolyse faster at high pH values.
As only the dissolved portion of the substance can be hydrolysed, the formation of the hydrolysis is expected to occur only to a minimum extent for poorly soluble substances.
Key value for chemical safety assessment
Additional information
A study could not be conducted because the substance is highly insoluble in water. As the substance is an UVCB, QSAR calculations were performed applying HYDROWIN model for five probable structures in order to provide an estimate on hydrolysis. Table 1 lists calculated Half-Life values in relation to the pH.
Table 1 QSAR calculations on Hydrolytical Half-Life for five different structures of the UVCB substance.
Structure |
1 |
2 |
3 |
4 |
5 |
pH |
Half-Life in days |
||||
5 |
17.6 |
17.8 |
14.6 |
15.6 |
15.6 |
6 |
17.6 |
17.8 |
14.6 |
15.6 |
15.6 |
7 |
17.6 |
17.7 |
14.5 |
15.6 |
15.6 |
8 |
16.9 |
17.1 |
13.6 |
14.8 |
14.8 |
9 |
12.5 |
12.8 |
8.5 |
9.91 |
9.9 |
10 |
3.5 |
3.6 |
1.8 |
2.3 |
2.3 |
Overall, it can be assumed that hydrolysis could theoretically take place. However, hydrolysis would be very slow and more likely at higher pH values. Whereas, hydrolysis is further considered to take place more slowly the lower the pH.
Experimental hydrolysis data is available for the similar substance CAS 597 -82 -0, which is also a triphenylphosphorothionate, but whithout alkyl chains. Half-lifes for hydrolyis of the phosphor thioester were determined to be 115 - 24 days at 25 °C and pH 4 -9 (ECHA disseminated data, accessed March 14, 2017). Whereas HYDROWIN calculation estimated 10 -3 days at pH 5 -9. Thus, HYDROWIN calculation can further be considered to rather underestimate Half-Life times for this phosphorus thioester group.
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