Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

The mutagenic activity of benzothiazole was investigated in a bacterial gene mutation assay conducted comparable to OECD-guideline 471 with acceptable restrictions (only 4 strains used). The plate incorporation method was performed with Salmonella typhimurium TA98, TA 100, TA1535 and TA1537 both in presence and absence of a metabolic activator at 8, 40, 125, 200, 250, 500, 1000, 2000, 4000, 5000 µg benzothiazole per plate. Under these conditions no mutagenic activity was reported in strains TA 98, TA 100, TA 1535, or TA1537 (Gahlmann, Bayer AG, 1991).

Short description of key information:
Benzothiazole is considered to be not genotoxic.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

No classification required.