Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
29 October 2008 - 9 January 2009
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study has been performed according to OECD and/or EC guidelines and according to GLP principles.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report Date:
2009

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
column elution method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): ASA404 C8
- Substance type: Off-white powder
- Physical state: Solid
- Analytical purity: 99.9%
- Impurities (identity and concentrations): not indicated
- Lot/batch No.: 082401
- Expiration date of the lot/batch: 22 February 2009
- Stability under test conditions: stable
- Storage condition of test material: at room temperature in the dark

Results and discussion

Water solubility
Water solubility:
1.35 mg/L
Temp.:
19.9 °C
pH:
7.2 - 7.3
Details on results:
No undissolved particles were detected in the eluates using the Tyndall effect. No test substance was detected in the samples from the blank column.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The column elution method was chosen for the determination of the water solubility of ASA404 C8. The water solubility of the test substance at 19.9°C +/- 0.4°C was 1.35 x 10-3 g/l. The pH of the aqueous samples was 7.2 - 7.3.