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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

Acutely harmful to aquatic invertebrates

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
46.9 mg/L

Additional information

Effects of the test item on mobility of daphnids were investigated in a 48 -h static study under GLP conditions and following OECD TG 202. Due to the low water solubility, the test concentrations were prepared as water accomodated fractions (WAF) as described in OECD TG 23. The test concentrations could not be chemically verified due to the lack of a sufficiently sensitive method to determine the test substance in the test solutions up to its saturation limit. Therefore, the results are based on loading rate ("nominal concentrations"). The 48 -h EL50 was 46.9 mg/L (BASF, 2011).

In an older study performed similarily to nowadays methods, but without analytical monitoring, effects on daphnids were determined using the analogous test substance Adogen 283 (di-iso-tridecylamine, DTDA, CAS 57157 -80 -9). Based on nominal concentrations, the 48 -h EC50 for effects on Daphnia magna was determined to be 0.236 mg/L (Dave et al., 1981). This study is regarded as of lower reliability as the key study since it was performed with a different mixture (Adogen 283) consisting indeed of the representative molecule (CAS 57157 -80 -9; purity 92%), but lacking the other fractions of the test item as defined in section 1. Moreover, details on test methods and results like test concentrations and their effects on mobility are not available. Also, only 1 replicate per concentration was set up.