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Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation / corrosion, other
Remarks:
no data
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
Data are used by the OECD Toolbox and can be considered as reliable peer-reviewed data.

Data source

Reference
Reference Type:
other: Danish EPA
Title:
Multicase model
Author:
HSDB
Year:
2000
Bibliographic source:
Data from RTECS nov. 2000, HSDB nov. 2000, and 22. Amendment of EU Annex I
Report date:
2000

Materials and methods

Principles of method if other than guideline:
No data on guideline
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
N-methylaniline
EC Number:
202-870-9
EC Name:
N-methylaniline
Cas Number:
100-61-8
Molecular formula:
C7H9N
IUPAC Name:
N-methylaniline

Test animals

Species:
other: no data
Strain:
not specified

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified
Duration of treatment / exposure:
No data
Observation period:
No data
Number of animals:
No data

Results and discussion

In vivo

Results
Irritation parameter:
other: Multicase model
Basis:
other: QSAR
Time point:
other: Not applicable
Score:
-1
Reversibility:
no data
Remarks on result:
other: Negative for skin irritation.

Applicant's summary and conclusion

Interpretation of results:
other: negative
Remarks:
Criteria used for interpretation of results: other: Danish EPA
Conclusions:
The substance is expected as non-irritating to skin.