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EC number: 283-041-9 | CAS number: 84539-53-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The 72 hour ErC50 value for EDDHMA-Fe with Selenastrum capricornutum was 71 mg/L and the ErC10 was 2.8 mg/L based on nominal concentrations and growth rate. Conclusions related to effects on algae should be used with care.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 71 mg/L
- EC10 or NOEC for freshwater algae:
- 2.8 mg/L
Additional information
One study with EDDHMA-Fe is available to study potential effects to algae and one study with the structurally related EDDHA-FeNa. Both substances cause a strong coloration of test solutions, limiting exposure to light, introducing difficulties in interpreting the results in a reliable manner. Also, the chelating properties could cause disturbances when micronutrients are deprived. In both studies no attempt was made to optimise micronutrient supply to exclude nutrient deprivation. The Bogers study concludes however on the minor effect of coloration, but whether the substance will interact with algae by contact can not be concluded (fish show coloration of fins when exposed). Both substances are expected to be readily photodegraded in lower concentrations, however only the Basf study indicates the decline of concentrations during the study. On the other hand, both studies conclude chronic toxicity end-points in the same order of magnitude and > 1 mg/L indicating they should not be considered hazardous to the aquatic environment.
- Key study with Selenastrum capricornutum (Bogers, 1996)
The study procedures described in this report were based on the EEC Directive 92/69, Publication No. L383 Part C-3 adopted December, 1992; OECD guideline No. 201, Adopted June 7, 1984; and IS0 Standard 8692, First edition, 15 November 1989.
The results showed that no inhibition of cell growth occurred when algal suspensions were exposed to light filtered through colored solutions up to 100 mg/L. A final EC50 -test was performed exposing exponentially growing algal cultures to EDDHMA- FeNa concentrations ranging from 1.0 to 100 mg/L. Cell densities were based on microscopical counting. At the start of the test, the actual test concentrations were in agreement with nominal (96 -101%). At the end of the 72 -hour period the measured concentration had not decreased by more than 20% in any of the samples analysed.
The color of the test solutions did not significantly contribute to the effect on algal growth. The EC50 for growth rate reduction (ErC50: 0 -72h) was a factor of 5 higher than the EbC50 :0 -72h, i.e. 71 mg/L (95% confidence limits: 54 and 93 mg/L), whereas the ErC10:0 -72h was only a factor of 2 higher (2.8 mg/L). The EC50 for inhibition of total cell growth (EbC50: 0 -72h) was 14 mg/L with a 95% confidence interval ranging from 10 to 22 mg/L. The EC10 for cell growth (EbC10: 0 -72h) was 1.4 mg/L.
- In a supporting study the the toxic effects of EDDHA-FeNa (Basf, 2010) on the growth of single-cell green algae as representatives of primary producers in freshwater plankton over a 72 hour static exposure period were determined according to the principles of OECD-Guideline 201 and EU method C.3.
Mean measured concentrations were considered to be an accurate representation of exposure levels throughout the exposure period. The 72 hour EC50 value for FeEDDHA with the Desmodesmus subspicatus CHODAT (SAG 86.81) was greater than 294 mg/L and the NOEC was 8.2 mg/L based on mean measured concentrations and growth rate. The 72 hour EC50 based on yield and mean measured concnetrations was 27.3 mg/L and the NOEC was 2.4 mg/L.
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