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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

No effects up to the limit of water solubility based on available data (EU Method C.2).

Key value for chemical safety assessment

Additional information

Since no studies investigating the short-term toxicity to aquatic invertebrates of (Z)-octadec-9-enyl oleate (CAS 3687-45-4) are available for this endpoint, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read across to the structurally related category member fatty acids, C16-18, C12-18-alkyl esters (CAS 95912-87-1) was conducted. The read-across substance fatty acids, C16-18, C12-18-alkyl esters is a UVCB substance covering (Z)-octadec-9-enyl oleate with its structural variability. This read-across is justified in detail in the overall summary (IUCLID section 6.1) and within the category justification in IUCLID Section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was used for the assessment. Nevertheless, as it can be seen in the data matrix of the category justification in section 13 and the overall summary, all reliable data in the category support the hazard assessment of each category member by showing a consistent pattern of results.

The study with the read-across substancefatty acids, C16-18, C12-18-alkyl esterswas conducted according to EU Method C.2 (GLP) under static conditions with the water flea Daphnia magna (Wierich, 2001). A Water Accommodated Fraction of nominal 100 mg/L was tested in this study. Measured concentrations were in the range of 0.1 - 0.2 mg/L or even below the detection limit (GC analysis). After 48 h no effects on the test organisms were observed resulting in an EL50 > 100 mg/L (nominal).

Based on the result from one structurally related read-across substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) which is characterized by a similar ecotoxicological profile and comparable structure, it can be concluded that (Z)-octadec-9-enyl oleate will not exhibit short-term effects to aquatic invertebrates up to the limit of water solubility.