Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In the literature a patch test and a photopatch test with 5% butyl flufenamate ointmentin in human patients are described.

Flufenaminsäurebutylester (butyl flufenamate) was negative in both publications.


Migrated from Short description of key information:
No internal sensitization studies were conducted with Flufenaminsäurebutylester:
Results of sensitization studies with Flufenaminsäurebutylester were found in the literature (May 2011):

Patch test (human) butyl flufenamate 5% ointment: negative
(Kubo, Y. et al. (1986); Contact Dermatitis v. 15, p. 109-111)

Photopatch test (human) butyl flufenamate 5% ointment: negative
(Kurumaji, Y. et al. (1991); Contact Dermatitis v. 25, p. 218-223)

Justification for classification or non-classification

Based on the study results a classification according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008 (CLP) is not required.