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EC number: 289-222-9 | CAS number: 86290-83-7 A complex combination of hydrocarbons obtained by the distillation of steam cracked tar. It consists predominantly of aromatic and other hydrocarbons and organic sulfur compounds boiling in the range of approximately 210°C to 340°C (410°F to 644°F).
Clear bacteriotoxic effect (reduced his- background growth, decrease in the number of his+ revertants) at doses ≥200 µg/plate.
Rohnaphthalin-gemisch (CAS 85117-10-8) was tested in a bacterial reverse mutation test using Salmonella typhimurium tester strains TA98, TA100, TA1535 and TA1537 in the presence and absence or Aroclor-induced rat liver S9.
Toxicity was observed with some conditions at > 200 µg/plate. Small increases in revertant colonies seen in strains TA98 and 100, in only some of the experiments, were not seen on changing the test conditions (pre-incubation test to try to optimise any activity that may be present). The increases in revertant colonies seen do not meet the criteria for a positive response and are considered not to indicate a mutagenic effect of the test material.
Rohnaphthalin-gemisch (CAS 85117-10-8) did not induce a significant increase in revertant colonies in Salmonella strains with or without rat liver metabolic activation at any dose level and is considered not to be a mutagen in this test system.
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