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Toxicological information

Genetic toxicity: in vitro

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Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
other: SNIF#001-4.3-10-01
Title:
Unnamed
Report date:
1989

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Ames
GLP compliance:
yes
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2'-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)
EC Number:
403-800-1
EC Name:
2,2'-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)
Cas Number:
103597-45-1
Molecular formula:
C41H50N6O2
IUPAC Name:
2,2'-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)
Constituent 2
Reference substance name:
2,2'-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl) phenol)
IUPAC Name:
2,2'-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl) phenol)

Method

Species / strain
Species / strain / cell type:
bacteria, other: Salmonella typhimurium strains TA 98, TA 100, TA 1535, TA 1537, TA 1538

Results and discussion

Additional information on results:
Negative with and without metabolic activation

Any other information on results incl. tables

Comments:

Negative with and without metabolic activation.

Applicant's summary and conclusion

Conclusions:
Negative with and without metabolic activation