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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Genetic toxicity: in vitro

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Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
other: SNIF#001-4.3-10-01
Title:
Unnamed
Report date:
1989

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Ames
GLP compliance:
yes
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2'-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)
EC Number:
403-800-1
EC Name:
2,2'-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)
Cas Number:
103597-45-1
Molecular formula:
C41H50N6O2
IUPAC Name:
2-(2H-1,2,3-benzotriazol-2-yl)-6-{[3-(2H-1,2,3-benzotriazol-2-yl)-2-hydroxy-5-(2,4,4-trimethylpentan-2-yl)phenyl]methyl}-4-(2,4,4-trimethylpentan-2-yl)phenol
Constituent 2
Reference substance name:
2,2'-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl) phenol)
IUPAC Name:
2,2'-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl) phenol)

Method

Species / strain
Species / strain / cell type:
bacteria, other: Salmonella typhimurium strains TA 98, TA 100, TA 1535, TA 1537, TA 1538

Results and discussion

Additional information on results:
Negative with and without metabolic activation

Any other information on results incl. tables

Comments:

Negative with and without metabolic activation.

Applicant's summary and conclusion

Conclusions:
Negative with and without metabolic activation