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Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: guidance followed, no GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Pyrene
EC Number:
204-927-3
EC Name:
Pyrene
Cas Number:
129-00-0
Molecular formula:
C16H10
IUPAC Name:
pyrene

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
ca. 5.43
Temp.:
30 °C
pH:
>= 5 - <= 8
Details on results:
Standard deviation: 0.24
Average Partition Coefficient (n-octanol/water): 5.43 ± 0.24

Applicant's summary and conclusion