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EC number: 200-893-9
CAS number: 75-71-8
Quevauviller et al. (1964) and Quevauviller (1965) applied CFC-11,
CFC-12, CFC-114, and mixtures of CFC-11 and CFC-12 and of CFC-11 and
CFC-22 were applied once a day, 5 days/week for 1 month to the eye of
irritation only was noted in the eye of the rabbits; the effects are not
considered to result in classification. The
study cites an exposure period of 1 month, which is above the specified
exposure time requirements of the current guidelines. Hence
the results are deemed to be appropriate.
should be noted that the substance is a gas, and as such, prolonged
exposure to the eye is not anticipated. Following
exposure, evaporation would occur, resulting in rapid removal from the
site, hence minimising the effects of acute exposure.
should also be noted that in accordance with section 2 of REACH Annex
XI, the study does not need to be conducted as the substance is a gas. Hence
the data provided is considered appropriate for assessment of this
endpoint as supporting information only.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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