Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1999

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2-difluoro-1,3-benzodioxole
EC Number:
216-431-4
EC Name:
2,2-difluoro-1,3-benzodioxole
Cas Number:
1583-59-1
Molecular formula:
C7H4F2O2
IUPAC Name:
2,2-difluoro-2H-1,3-benzodioxole

Sampling and analysis

Analytical monitoring:
no

Test organisms

Test organisms (species):
activated sludge

Study design

Limit test:
no
Total exposure duration:
3 h

Results and discussion

Effect concentrations
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
5 360 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Remarks:
respiration rate
Remarks on result:
other: The EC values are determined by statistical methods (probit analysis)

Applicant's summary and conclusion

Conclusions:
Test substance EC50 = 5360 mg/L