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EC number: 292-564-1 | CAS number: 90640-45-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
One chronic earthworm test (OECD 222, GLP, reliability 2) has been performed with the hydrogenated diamine C16 -18 (CAS 133779-11-0). Effects on mortality, biomass and reproduction were not observed. Therefore the NOECearthworm is equal to the highest test concentration of 1000 mg a.i./kg soil dw after 56 days of exposure.
Key value for chemical safety assessment
- Long-term EC10, LC10 or NOEC for soil macroorganisms:
- 1 000 mg/kg soil dw
Additional information
Effects of hydrogenated diamine C16 -18 (CAS 133779-11-0) on mortality, biomass and the reproductive potential of the earthworm species Eisenia fetida fetida (Savigny) were determined according to the guidelines DIN ISO 11268 -2 (1998), OECD 222 (2004) and BBA (1994). The study was conducted under static conditions over 8 weeks with the four different application rates 125 - 250 - 500 - 1000 mg/kg soil dry weight (DW) mixed with natural soil (fresh LUFA 2.2). Eighty adult earthworms with clitellum in control and 40 test organisms in vehicle control and test item concentrations with an individual weight of 0.35 to 0.60 g, divided into eight and four replicates, respectively were inserted. For statistical evaluation, control and vehicle control were pooled because analysis of variance showed no significant differences between controls.
After 28 days no significant differences occurred concerning mortality, pathological symptoms or behaviour of the adult earthworms at all tested application rates and in the control groups. The individual body live weights increased in the control as well as in the test item groups. After a further 28 days the reproduction (average number of juveniles) ranged from 291 to 344 in the control groups and from 271 to 333 juveniles in the test item groups, respectively. There was no statistically significant change of mortality, biomass and reproduction compared to the pooled control at all application rates. The validity criteria recommended by the test guidelines were fulfilled. The NOEC after 56 days was 1000 mg/kg soil dw for mortality, reproduction and biomass. The corresponding LOEC was > 1000 mg/kg soil dw.
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