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Diss Factsheets
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EC number: 600-026-8 | CAS number: 1000817-22-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: Municipal activated sludge from a wastewater treatment plant.
- Preparation of inoculum for exposure: a aliquot of activated sludge suspension was sieved (mesh size = 1mm). After settling the supernatant was discarded and sludge was filled up with water.
- Concentration of sludge: 6 g/L - Duration of test (contact time):
- 28 d
- Initial conc.:
- 20 mg/L
- Based on:
- other: TOC
- Initial conc.:
- 30 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: 1500 ml test solution contained ca. 30 mg/L test substance (44.8 mg/vessel, 20 mg/L TOC), 19.5 ml mineral medium, 7.5 ml inoculum
- Test temperature: 22 ± 2 °C
- pH:
- study initation: 7.4
- study end: 7.2 - 7.3
TEST SYSTEM
- Culturing apparatus: 2 L incubation bottles, filled up to a volume of 1.5 L
- Number of culture flasks/concentration: 3
- Method used to create aerobic conditions: aeration performed with CO2 free air at a flow of approx. 800 ml per hour
- Details of trap for CO2 and volatile organics if used: Bottles were connected to two serial scrubbing bottles (total volume 250 ml) filled with 100 ml 0.05 sodium hydroxide solution.
SAMPLING
- Sampling frequency: twice a week
CONTROL AND BLANK SYSTEM
- Inoculum blank: 2
- Inhibition control: 1
- Reference substance: 1
- Reference substance:
- aniline
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 60 - 70
- Sampling time:
- 28 d
- Details on results:
- - 10-day window was failed
- Duration of the adaption phase: 2 d
- Degradation degree of the inhibition control after 14 days: 67% - Results with reference substance:
- - Degradation degree of the reference substance after 14 days: 71%
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
Reference
Since Kerocom FM 38 is a mixture, the application of the 10-day window criterion is not scientifically justified.
Description of key information
Readily biodegradable: >60% CO2 evolution in 28 days (OECD 301B)
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
In a CO2 evolution test according to OECD guideline 301 B the biodegradation of the test substance was investigated (BASF SE, 2009). After 28 days > 60 % degradation was determined. The degradation degree was not reached within the 10 - day window; however, the application of the 10-day window criterion is not scientifically justified for UVCB substances since sequential degradation can be assumed. Exceeding the pass level (60 % Degradation based on CO2 evolution) within the standard test duration of 28 days is considered to be sufficient to evaluate the described UVCB substance as readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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