Registration Dossier
Registration Dossier
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EC number: 214-185-2 | CAS number: 1111-78-0
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No data on long-term toxicity on fish are available. The long-term toxicity of ammonium carbamate to aquatic invertebrates can however be evaluated using the data on chronic toxicity to fish available for ammonium chloride and bicarbonate ions. The rationale for the read-across approach is descibed in the general discussion on aquatic toxicity. The key value selected refers to the chronic toxicity of ammonium chloride to Daphnia magna.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 4.81 mg/L
Additional information
In Annex IX of Regulation (EC) No 1907/2006, it is laid down that chronic toxicity tests shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects on aquatic invertebrates. According to Annex I of this regulation, the chemical safety assessment triggers further action when the substance or the preparation meets the criteria for classification as dangerous according to Directive 67/548/EEC or Directive 1999/45/EC or is assessed to be a PBT or vPvB. The hazard assessment of ammonium carbamate reveals neither a need to classify the substance as dangerous to the environment, nor is it a PBT or vPvB substance, nor are there any further indications that the substance may be hazardous to the environment. Therefore, a long-term toxicity study on aquatic invertebrates is not provided.
The long-term toxicity of ammonium carbamate to aquatic invertebrates can however be evaluated using the data on chronic toxicity to invertebrates available for ammonium chloride and bicarbonate ions. The rationale for the read-across approach is descibed in the general discussion on aquatic toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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