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EC number: 274-986-8 | CAS number: 70892-34-1
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2021-09-07 to 2021-10-18
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Version / remarks:
- adopted July 27, 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: OECD guideline for the testing of chemicals: Water Solubility, Guideline No.: 105
- Version / remarks:
- adopted July 27, 1995
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- estimation method (solubility ratio)
- Partition coefficient type:
- octanol-water
- Analytical method:
- analysis (not specified)
- other: observation of undissolved particles (for octanol)
- Key result
- Type:
- log Pow
- Partition coefficient:
- < -1.6
- Temp.:
- 20 °C
- pH:
- > 0 - < 14
- Remarks on result:
- other: The pH is not particularly mentioned in the study report, however it is being assumed that the study was conducted under regular pH conditions.
- Details on results:
- Undissolved particles were still observed in the test item / n-octanol mixture at the concentration 5.2 mg test item / 2 L n-octanol after 24 hours, thus, the solubility of the examined test item batch in n-octanol is less than 2.6 mg/L. The solubility of the same batch in water is 114.4 mg/L. Based on these results the log Pow of < -1.6 is calculated.
- Conclusions:
- Based on the individual solubility of test item in n-octanol and water, the log Pow is <-1.6.
Reference
Description of key information
Based on the individual solubility of test item in n-octanol and water, the Pow is <0.023 and the log Pow < -1.6.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -1.6
- at the temperature of:
- 20 °C
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