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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: testing method performed according to OECD107

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
not specified
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
4'-ethoxy-3-hydroxy-2-naphthanilide
EC Number:
225-200-7
EC Name:
4'-ethoxy-3-hydroxy-2-naphthanilide
Cas Number:
4711-68-6
Molecular formula:
C19H17NO3
IUPAC Name:
N-(4-ethoxyphenyl)-3-hydroxy-2-naphthamide

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
2.8
Temp.:
23 °C
pH:
ca. 7

Any other information on results incl. tables

Table 1: Results in detail

determ. no.

  stock solution [ml]    n-octanol [ml]     test substance conc. in n-octanol phase [mg/l]     test substance conc. in water phase [mg/l]  log Pow   
  A1    5   10  661,4  0,62  3,0
  A2    5   10  638,9  1,17  2,7
  B1   10   10  634,6  1,14  2,7
  B2   10   10  653,5  0,97  2,8
  C1   20   10  657,2  1,31  2,7
  C2   20   10  646,2  1,42  2,7

mean

  ---   ---   ---   ---  2,8

Stock solution: 722 mg/l

Conc. of filtered stock solution: 665 mg/l

Applicant's summary and conclusion

Conclusions:
Due to the partition coefficient n-octanol-water bioaccumulation is not expected.

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