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EC number: 939-633-0 | CAS number: 705279-64-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LL50 (96 h) > 100 mg/L (nominal)(Danio rerio, EU Method C.1)
Key value for chemical safety assessment
Additional information
No experimental data evaluating the acute toxicity of Glycerides, C8-21 and C8-21-unsaturated, mono- and di-, acetates (C10)(CAS No. 97593-30-1) to fish are available. Therefore, read-across data from a structurally related category member, Glycerides, C8-21 and C8-21-unsaturated, mono- and di-, acetates (C12)(CAS No. 97593-30-1) is used in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Both substances are esters formed from the combination between acetylated fatty acids and glycerol as alcohol component. These two substances are structurally identical except for the length of their main fatty acid component (being either C10 or C12).The behaviour of these substances in the water phase is expected to be very similar based on their water solubility values (10.2-24.6 mg/L for the C10 and 3.5-21.9 mg/L for the C12 substances, respectively) and log Pow (> 4).
The acute toxicity of Glycerides, C8-21 and C8-21-unsatd., mono- and di-, acetates (C12)(CAS No. 97593-30-1) to fish species was investigated in two studies (Weyers, 2007 and Richter, 2012). Both tests were conducted according to EU Method C.1 (Acute Toxicity for Fish), under GLP conditions under a static and semi-static water regime respectively. In the first test (Weyers, 2007),Danio rerio was exposed to the test substance for 96 h at 22±1°C and the test concentration (limit test, 100 mg/L loading rate) measured at t=0 h, being below the limit of detection (LOD) of the GC method (< 0.062 mg/L). No effects were observed in test organisms after 96 hours (LL50 (96 h) > 100 mg/L (nominal)). A second study (Richter, 2012) was performed exposing Danio rerio to the test substance, this time under semi-static conditions. The test concentration (100 mg/L, nominal loading rate) was measured by GC analysis. GC analysis of dissolved and undissolved test solution at 100 mg/L before the final filtration step resulted in test concentrations close to nominal values. During the testing period (performed with the filtered test solutions, without the undissolved fraction), measured concentrations remained below the limit of detection (LOD) of both GC (0.070 mg/L) and DOC (2 mg/L) methods. The water solubility of the substance was tested at 100 and 1000 mg/L, resulting in values of 3.5 and 21.9 mg/L, respectively. Nevertheless, differences in solubility of substances in pure water (water solubility test) and test medium (aquatic test) can be expected. Furthermore, considering that Glycerides, C8-21 and C8-21-unsatd., mono- and di-, acetates is expected to show high adsorption potential (log Koc values 3.7-4.2), most probably a significant fraction of test material was adsorbed to the filter. However, since the Water Accomodated Fraction (WAF) was performed, probably the adsorbed fraction of the substance also corresponded to the undissolved test material, and only the water soluble fraction was present in the test solution. Once again, no adverse effects were observed at the concentration tested and the LL50 (96 h) was determined to be > 100 mg/L (nominal).
Based on the results obtained for the structurally similar analogue substance (in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5) no effects up to the maximum achievable concentration in test medium are expected for Glycerides, C8-21 and C8-21-unsaturated, mono- and di-, acetates (C10).
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