Registration Dossier
Registration Dossier
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EC number: 258-053-2 | CAS number: 52628-03-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
One 72-hour algal study, using Pseudokirchneriella subcapitata
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 30 mg/L
Additional information
The purpose of this study was to assess the effects of the reaction product of 2- hydroxyethyl methacrylate (HEMA) and polyphosphoric acid (PPA), hereafter referred to as HEMA Phosphate, to the freshwater green alga, Pseudokirchneriella subcapitata, over a 72-hour static exposure period. These data were used to determine EC50 (the concentration causing 50% inhibition) values for 72-hour cell density, 0-72-hour cell yield, and 0-72-hour average specific growth rate. No-observable-effect concentrations (NOEC) were determined for each endpoint based on the highest concentration not significantly different from the control. Test solutions were analytically verified at initiation and termination by LC/MS. The mean measured concentrations were , 3.75, 7.60, 15.0, 29.0, 60.1 and 119 mg HEMA Phosphate/L. The results of the test are as follows:
72 -hour cell density: EC50 >120 mg/L; NOEC = 30 mg/L
0 -72 -hour cell yield: EyC50 > 120 mg/L; NOEC = 30 mg/L
0 -72 hour growth inhibition ErC50 > 120 mg/L; NOEC = 30 mg/L
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