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Diss Factsheets
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EC number: 224-339-0 | CAS number: 4316-74-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
According to the calculation by the EPI Suite by using the models BioWin3 and BioWin5, the criteria for readily biodegradable are BioWin3: weeks or faster and BioWin5: probability is >= 0.5. For sodium N-methyltaurinate, the result of BioWin3 is weeks while the result of BioWin5 is < 0.5. Therefore, the substance should be classified as not readily biodegradable.
However, further empirical studies show that the read-across substance N-methyltaurine is readily biodegradable according to an OECD 301C guideline study (62 % BOD after 28 days). N-methyltaurinate is the deprotonated form of N-methyltaurine. Both sodium N-methyltaurinate and N-methyltaurine are highly soluble in water. Therefore, it is expected that both substances can be degraded by comparable mechanisms in aqueous solution. Hence, the data on N-methyltaurine provide a reasonable measure for the biodegradability of sodium N-methyltaurinate. We conclude that sodium N-methyltaurinate is readily biodegradable. This result is also supported by further read-across substances.
Additional information
According to the calculation by the EPI Suite by using the models BioWin3 and BioWin5, the criteria for readily biodegradable are BioWin3: weeks or faster and BioWin5: probability is >= 0.5. For sodium N-methyltaurinate, the result of BioWin3 is weeks while the result of BioWin5 is < 0.5. Therefore, the substance should be classified as not readily biodegradable.
The guideline study according to OECD 301C shows that the read-across substance N-methyltaurine is readily biodegradable (62 % BOD after 28 days). This result is supported by the two guideline studies according to OECD 301B, which show that the read-across substances sodium N-methyl oleoyl taurinate and sodium N-methyl cocoyl taurinate, derivatives are readily biodegradable. This is supported by the handbook data of the J-CHECK database on sodium methyl oleoyl taurate. Further data on N-methyltaurine published by Levine et al. describe the substance to be rapidly biodegradable by plant rhizosphere microbes, although the biodegradation rate is not reported. N-methyltaurinate is the deprotonated form of N-methyltaurine. Both sodium N-methyltaurinate and N-methyltaurine are highly soluble in water. Hence, it is expected that both substances can be degraded by comparable mechanisms in aqueous solution. Therefore, the experimental OECD guideline study on N-methyltaurine provides a reasonable measure for the biodegradability of sodium N-methyltaurinate. In conclusion, sodium N-methyltaurinate is readily biodegradable.
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