Registration Dossier
Registration Dossier
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EC number: 691-719-4 | CAS number: 1072957-71-1
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
SYN545192 was negative for skin sensitisation potential in the mouse local lymph node assay.
Migrated from Short description of key information:
SYN545192 is not a skin sensitiser nor is it considered to have potential to cause respiratory sensitisation
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
SYN545192 is considered not to be a respiratory sensitiser based on its lack of skin sensitisation potential and also the lack of any structural alerts for respiratory and skin sensitisation potential (DEREKTM: Version 2.0.2.201111291322; February 2012)
Migrated from Short description of key information:
SYN545192 is judged not to be a respiratory sensitiser
Justification for classification or non-classification
Based on the available information the substance does not meet the criteria for classification as "skin sensitiser" under Regulation (EC) 1272/2008, Annex I, Part 3, 3.4.2.2; reason for non-classification: conclusive but not sufficient for classification.
Based on the available information the substance does not meet the criteria for classification as "respiratory sensitiser" under Regulation (EC) 1272/2008, Annex I, Part 3, 3.4.2.1; reason for non-classification: inconclusive.
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