Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Two Klimisch-1-rated studies on acute oral and dermal toxicities have been conducted. The oral LD50 value of the substance = 1406 mg/kg body weight. The dermal LD50 > 2000 mg/kg bw.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
1 406 mg/kg bw

Additional information

The oral LD50 value of the substance in rats was 1406 mg/kg body weight for the sexes combined and 1571 mg/kg body weight for males alone. The estimated value for females alone was 1228 mg/kg body weight.

The dermal LD50 value of the substance in rats was established as exceeding 2000 mg/kg body weight.

Justification for classification or non-classification

According to the new CLP regulation (EU version of the UN GHS), with an oral LD50 between 300 and 2000 mg/kg the substance falls under classification "acute oral. tox. category 4". Based on the former EEC Directive 83/467/ECC the substance is classified as Xn, R22, harmful. No classification of the test item as to its dermal toxicity properties.