Registration Dossier
Registration Dossier
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EC number: 407-230-4 | CAS number: 126637-70-5 BLUE GS 1259 R5
Endpoint summary
Administrative data
Description of key information
Two Klimisch-1-rated studies on acute oral and dermal toxicities have been conducted. The oral LD50 value of the substance = 1406 mg/kg body weight. The dermal LD50 > 2000 mg/kg bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 1 406 mg/kg bw
Additional information
The oral LD50 value of the substance in rats was 1406 mg/kg body weight for the sexes combined and 1571 mg/kg body weight for males alone. The estimated value for females alone was 1228 mg/kg body weight.
The dermal LD50 value of the substance in rats was established as exceeding 2000 mg/kg body weight.
Justification for classification or non-classification
According to the new CLP regulation (EU version of the UN GHS), with an oral LD50 between 300 and 2000 mg/kg the substance falls under classification "acute oral. tox. category 4". Based on the former EEC Directive 83/467/ECC the substance is classified as Xn, R22, harmful. No classification of the test item as to its dermal toxicity properties.
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