Registration Dossier
Registration Dossier
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EC number: 407-230-4 | CAS number: 126637-70-5 BLUE GS 1259 R5
Endpoint summary
Administrative data
Description of key information
Two Klimisch-1-rated studies on acute oral and dermal toxicities have been conducted. The oral LD50 value of the substance = 1406 mg/kg body weight. The dermal LD50 > 2000 mg/kg bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 1 406 mg/kg bw
Additional information
The oral LD50 value of the substance in rats was 1406 mg/kg body weight for the sexes combined and 1571 mg/kg body weight for males alone. The estimated value for females alone was 1228 mg/kg body weight.
The dermal LD50 value of the substance in rats was established as exceeding 2000 mg/kg body weight.
Justification for classification or non-classification
According to the new CLP regulation (EU version of the UN GHS), with an oral LD50 between 300 and 2000 mg/kg the substance falls under classification "acute oral. tox. category 4". Based on the former EEC Directive 83/467/ECC the substance is classified as Xn, R22, harmful. No classification of the test item as to its dermal toxicity properties.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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