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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Type of information:
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Validated QSAR model
Principles of method if other than guideline:
Calculation based on HYDROWIN v2.00, Estimation Programs Interface Suite™ for Microsoft® Windows v 4.10. US EPA, United States Environmental Protection Agency, Washington, DC, USA.
GLP compliance:
Estimation method (if used):
- Total Kb for pH > 8: 4.95 E-003 L/mol sec
- Temperature for which rate constant was calculated: 25 °C
- Computer programme: HYDROWIN v2.00
Transformation products:
not measured
25 °C
44.299 yr
25 °C
4.43 yr
Details on results:
For detailed description on the model and its applicability, see "Any other information on materials and methods incl. tables".

Result refers to the uncharged molecule.

Description of key information

Hydrolysis is not a relevant degradation process (DT50 > 1 yr at pH7).

Key value for chemical safety assessment

Additional information

No experimental studies investigating the hydrolysis of isodecyl pivalate (CAS 60209-82-7) are available. Reliable QSAR calculations performed for the substance using HYDROWIN v2.00 indicate that hydrolysis is a negligible degradation pathway in the environment. DT50 values of 44.3 yr at pH7 and 4.4 yr at pH8 were calculated. Moreover, due to the physico-chemical properties of the substance like the very low water solubility (< 0.05 mg/L, i.e. below the analytical detection limit) it is considered to be technically not possible to perform a hydrolysis study due to the lack of suitable analytical methods.