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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1980
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
other: Method - A-11
Deviations:
not specified
GLP compliance:
no
Specific details on test material used for the study:
None
Analytical monitoring:
no
Details on sampling:
None
Vehicle:
no
Details on test solutions:
None
Test organisms (species):
other: Trout fishes
Details on test organisms:
- 8 trouts were used to performed the experiment.
Test type:
not specified
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Post exposure observation period:
None
Hardness:
No data
Test temperature:
16 °C
pH:
7.9 to 8.1
Dissolved oxygen:
No data
Salinity:
not applicable because freshwater used.
Nominal and measured concentrations:
Nominal concentration: 30.0, 100.0, 300.0 mg/l
Details on test conditions:
None
Reference substance (positive control):
no
Duration:
48 h
Dose descriptor:
LC0
Effect conc.:
30 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
58 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC100
Effect conc.:
100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC0
Effect conc.:
< 30 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
43 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Details on results:
- 30.0 mg/l: all 8 fishes were alive at 4, 24, 48 and 72 hours exposure time. After 96 hours exposure, 5 fishes were alive.
- 100.0 mg/l: 4 hours exposure, 8 fishes alive, only 1 left alive at 24 hours exposure time and by 48 hours, all fishes were died.
- 300.0 mg/l: No survivor after 4 hours exposure time.
Results with reference substance (positive control):
None
Reported statistics and error estimates:
None
Sublethal observations / clinical signs:

None

Validity criteria fulfilled:
not specified
Conclusions:
The LC50 in this acute fish toxicity test was determined to be 43 mg/l after 96 hours exposure time.
Executive summary:

FAT 20242/A was evaluated for Fish toxicity according to methodology similar to OECD 203. 8 trout fish in each group were exposed in fresh water to FAT 20242/A at 30, 100 and 300 mg/L. At 100 mg/L, 5 out of 8 fish survived. At 100 and 300 mg/L, all the exposed fish died by 48 hours. Hence based on these findings, the LC50 in this acute fish toxicity test was determined to be 58 mg/l (48 hours exposure time) and 43 mg/l after 96 hours exposure time.

Description of key information

The LC50 in fish was determined to be 58 mg/l (48 hours exposure time) and 43 mg/l after 96 hours exposure time.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
43 mg/L

Additional information

Several studies were carried out to determine the acute fish toxicity using methodology similar to OECD Guideline 203. The LC50 in the key acute fish toxicity test was determined to be 58 mg/l (48 hours exposure time) and 43 mg/l after 96 hours exposure time. The LC50 in the supporting acute fish toxicity tests were determined to be 192 mg/l, 204 mg/l and 549.51 mg/l (48 hours exposure time) and 170 mg/l, 157.1 mg/l and 481.75 mg/l after 96 hours exposure time.