Registration Dossier
Registration Dossier
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EC number: 619-566-0 | CAS number: 848301-65-5
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP-study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Safepharm Laboratories Limited
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
Study design
- Analytical method:
- gas chromatography
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- > 6.5
- Temp.:
- 20 °C
- pH:
- ca. 7
Any other information on results incl. tables
see attached full study report at "4.2 Melting Point" [ Attachment 6, page 21-28]
Applicant's summary and conclusion
- Conclusions:
- partition coefficient: log Pow = 4.40 to >6.50 at 20°C (by percentage area normalisation, 60.2% of the test material had a log Pow value greater than 6.50)
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