Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
sub-chronic toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
other: Safety Data Sheet

Data source

Reference
Reference Type:
publication
Title:
Sikkerhedsdatablad Isopropylamin, Oxea
Author:
Oxea
Year:
2011

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 413 (Subchronic Inhalation Toxicity: 90-Day Study)

Test material

Constituent 1
Chemical structure
Reference substance name:
Isopropylamine
EC Number:
200-860-9
EC Name:
Isopropylamine
Cas Number:
75-31-0
Molecular formula:
C3H9N
IUPAC Name:
propan-2-amine

Test animals

Species:
rat
Sex:
male/female

Results and discussion

Effect levels

Dose descriptor:
NOAEC
Effect level:
500 mg/m³ air
Sex:
male/female

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
The subcronic toksicity for male/femate rats by inhalation is NOEAC (90 d): 500 mg/m3.