Registration Dossier
Registration Dossier
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EC number: 204-875-1 | CAS number: 128-03-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (3 h) = 3.65 mg a.i./L
Key value for chemical safety assessment
Additional information
Studies investigating the toxicity of KDDC (CAS No. 128-03-0) to aquatic microorganisms are not available. Therefore, a conclusion about this endpoint had to be drawn based on results from a test performed with an analogue substance. The toxicity of SDDC (CAS No. 128-04-1) to activated-sludge microorganisms was tested by Van der Kerken (2003). The study was conducted according to OECD Guideline No. 209, Activated Sludge, Respiration Inhibition Test (1984), under GLP conditions. Activated sludge from a plant treating predominantly domestic waste was exposed to the test material for 3 hours at six different concentrations. The results showed that the test substance had a significant effect on respiration rate of microorganisms, obtaining EC10 and EC50 values of 0.25 and 3.65 mg a.i./L respectively.
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