Registration Dossier
Registration Dossier
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EC number: 218-145-5 | CAS number: 2052-25-7
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Testing for sensitizing properties of Diamantechtrot BT was performed in female guinea pigs according to the method of MAGNUSSON & KLIGMAN.
Intradermal induction was performed using 5 % Diamantechtrot BT in deionized water.
Dermal induction and challenge treatment were carried out with 25 % Diamantechtrot BT in deionized water.
The validity of the test system is confirmed by the periodically conducted positive control test using alpha-hexyl cinnamic aldehyde for the maximization test (report number 99.0220, dated May 14, 1999; Hoechst Marion Roussel Deutschland GmbH, ProTox).
Under the conditions of the present study, none of ten animals of the treatment group showed a positive skin response after the challenge procedure.
Based on the results of this study Diamantechtrot BT showed no evidence for sensitizing properties.
Migrated from Short description of key information:
Under the conditions of the present study, none of ten animals of the treatment group showed a positive skin response after the challenge procedure. Based on the results of this study Diamantechtrot BT showed no evidence for sensitizing properties.
Justification for classification or non-classification
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