Registration Dossier
Registration Dossier
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EC number: 281-897-8 | CAS number: 84057-80-7
Toxicological Summary
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 16.76 mg/m³
DNEL related information
- Dose descriptor starting point:
- other: Derivation of the inhalation DNELs for zirconium propionate is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and propionic acid).
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 16.76 mg/m³
DNEL related information
- Dose descriptor:
- other: Derivation of the inhalation DNELs for zirconium propionate is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and propionic acid).
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 17.3 mg/kg bw/day
DNEL related information
- Dose descriptor starting point:
- other: Derivation of the dermal DNELs for zirconium propionate is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and propionic acid).
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
Workers - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - workers
In order to evaluate toxicological properties of the substance zirconium propionate, information on the assessment entities zirconium cation and propionate anion were considered. For a documentation and justification of that approach, please refer to the separate document attached to section 13, namely Read Across Assessment Report for zirconium propionate.
General Population - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 3.03 mg/m³
DNEL related information
- Dose descriptor starting point:
- other: Derivation of the inhalation DNELs for zirconium propionate is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and propionic acid).
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 3.03 mg/m³
DNEL related information
- Dose descriptor:
- other: Derivation of the inhalation DNELs for zirconium propionate is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and propionic acid).
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 8.65 mg/kg bw/day
DNEL related information
- Dose descriptor starting point:
- other: Derivation of the dermal DNELs for zirconium propionate is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and propionic acid).
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
General Population - Hazard via oral route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 1.63 mg/kg bw/day
DNEL related information
- Dose descriptor starting point:
- other: Derivation of the oral DNELs for zirconium propionate is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and propionic acid).
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - General Population
In order to evaluate toxicological properties of the substance zirconium propionate, information on the assessment entities zirconium cation and propionate anion were considered. For a documentation and justification of that approach, please refer to the separate document attached to section 13, namely Read Across Assessment Report for zirconium propionate.
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